Continuous Flow Chemistry: A Novel Technology for the Synthesis of Marine Drugs
Laura F. Peña, Paula González-Andrés, Lucía G. Parte, Raúl Escribano, Javier Guerra, Asunción Barbero, Enol López
Therapeutic Potential of Heterocyclic Compounds Targeting Mitochondrial Calcium Homeostasis and Signaling in Alzheimer’s Disease and Parkinson’s Disease
Victor Tapias, Paula González-Andrés, Laura F. Peña, Asunción Barbero, Lucía Núñez, Carlos Villalobos
Changing the reaction Pathway of Silyl-Prins Cyclization by Switching the Lewis acid: Application to the Synthesis of an Antinociceptive Compound
Carlos Díez-Poza, Laura Fernández-Peña, Paula González-Andrés, Asunción Barbero
Diastereoselective Synthesis of cis-2,6-disubstituted Dihydropyrane Derivatives Through a Competitive Silyl-Prins Cyclization versus Alternative Reaction Pathways
Laura F. Peña, Enol López, Ángel Sánchez-González, Asunción Barbero
Recent Advances in Biologically Active Coumarins from Marine Sources: Synthesis and Evaluation
Laura Fernández-Peña, Maria João Matos, Enol López
The Tetrahydrofuran Motif in in Marine Lipids and Terpenes
Paula González-Andrés, Laura Fernández-Peña, Carlos Díez-Poza, Asunción Barbero
The Tetrahydrofuran Motif in Polyketide Marine Drugs
Laura Fernández-Peña, Carlos Díez-Poza, Paula González-Andrés, Asunción Barbero
Bicyclic 5-6 Systems: Four Heteroatoms 3:1
Carlos Díez-Poza, Héctor Barbero, Laura Fernández-Peña, Asunción Barbero
Influence of the Substituents on the Opening of Silylepoxy Alcohols: 5-exo-Cyclization towards Tetrahydrofurans vs. Unexpected Side Reaction Leading to Tetrahydropyrans
Carlos Díez-Poza, Asunción Barbero
Unexpected Domino Silyl-Prins/Aryl Migration Process from Geminal Vinylsilyl Alcohols
Carlos Díez-Poza, Asunción Barbero
Marine Heterocyclic Compounds That Modulate Intracellular Calcium Signals: Chemistry and Synthesis Approaches
Paula González-Andrés, Laura Fernández-Peña, Carlos Díez-Poza, Carlos Villalobos, Lucía Núñez, Asunción Barbero
Intramolecular Cyclization of Alkenyl Alcohols: Towards the Synthesis of Oxacycles
Paula González-Andrés, Carlos Díez-Poza, Laura Fernández-Peña, Alberto Cherubin, Yolanda Blanco, Asunción Barbero
Organosilanes in the synthesis of saturated heterocycles
Carlos Díez-Poza, Laura Fernández-Peña, Alberto Cherubin, Juan Lión-Villar, Asunción Barbero
The silyl-Prins reaction as an emerging method for synthesis of heterocycles
Carlos Díez-Poza, Héctor Barbero, Alberto Diez-Varga, Asunción Barbero
Synthesis of polysusbstituted tetrahydropyrans by stereoselective hydroalkoxylation of silyl alkenols: en route to tetrahydropyranyl marine analogs
Carlos Díez-Poza, Patricia Val, Francisco J. Pulido, Asunción Barbero
The oxepane motif in marine drugs
Héctor Barbero, Carlos Díez-Poza, Asunción Barbero
Modular de novo synthesis of unsimmetrical BODYPY Dyes possessing four different aryl substituents
Natalie Netz, Carlos Díez-Poza, Asunción Barbero, Till Opatz
Eur J. Org. Chem. 2017, 4580-4599
Synthesis of O- and N-heterocycles by silyl-Prins Cyclization of Allylsilanes
Carlos Díez-Poza, Asunción Barbero
Eur. J. Org. Chem. 2017, 4651-4665
Synthesis of Azepane Derivatives by Silyl-aza-Prins Cyclization of Allylsilyl Amines: Influence of the Catalyst in the Outcome of the Reaction
Asunción Barbero, Alberto Diez-Varga, Francisco J. Pulido, Alfonso González-Ortega
Org. Lett. 2016, 18, 1972-1975
From Silylated Trishomoallylic Alcohols to Dioxaspiroundecanes or Oxocanes: Catalyst and Substitution Influence
Asunción Barbero, Alberto Diez-Varga, Francisco J. Pulido
J. Org. Chem. 2016, 81, 2704−2712
Efficient access to polysubstituted tetrahydrofurans by electrophilic cyclization of vinylsilyl alcohols
Asunción Barbero, Héctor Barbero, Alfonso González-Ortega, Francisco J. Pulido, Patricia Val, Alberto Diez-Varga, Joaquín R. Morán
RSC Advances 2015, 5, 49541-49551
Competitive Silyl–Prins Cyclization versus Tandem Sakurai–Prins Cyclization: An Interesting Substitution Effect
Alberto Diez-Varga, Héctor Barbero, Francisco J. Pulido, Alfonso González-Ortega, Asunción Barbero
Chem. Eur. J. 2014, 20, 14112-14119
Multicomponent Prins Cyclization from Allylsilyl Alcohols Leading to Dioxaspirodecanes
Francisco J. Pulido, Alberto Diez-Varga, Asunción Barbero
Org. Lett. 2013, 15, 5234-5237
Efficiency of Acid- and Mercury-Catalyzed Cyclization Reactions in the Synthesis of Tetrahydrofurans from Allylsilyl Alcohols
Francisco J. Pulido, Asunción Barbero, Patricia Val, Alberto Diez, Alfonso González-Ortega
Eur J. Org. Chem. 2012, 5350-5356
One-Pot Synthesis of 2,7-Dioxabicyclo[2.2.1]heptanes from Oxoallylsilanes
Francisco J. Pulido, Asunción Barbero, Raquel Abad
Eur J. Org. Chem. 2011, 6974-6979
One-pot multicoupling reaction of silylcopper reagents, organolithium compounds and alpha,beta-unsaturated nitriles
Francisco J. Pulido, Asunción Barbero, Yolanda Blanco
Org. & Biomol. Chem. 2011, 9, 1454-1458
Seven-Membered Ring Formation from Cyclopropanated Oxo- and Epoxyallylsilanes
Francisco J. Pulido, Asunción Barbero, Pilar Castreño
J. Org. Chem. 2011, 76, 5850-5855
Synthesis of 3-Methylenecyclohexan-1-ols by Lewis Acid Catalyzed Cyclization of Epoxy-allylsilanes
Francisco J. Pulido, Asunción Barbero, Pilar Castreño
Eur J. Org. Chem. 2010, 1307-1313
Allene
Francisco J. Pulido, Pilar Castreño, Asunción Barbero
Encyclopedia of Reagents for Organic Synthesis, 2009, 1, pp. 150-155. WILEY
Silyl- and Stannylderivatives of Organocopper compounds
Francisco J. Pulido, Asunción Barbero
The Patai Series: The chemistry of Organocopper Compounds, Z. Rappoport and I. Marek Eds., Part II, Chap. 16, pp. 775-856, 2009, John Wiley & Sons, Chichester, U.K.
Pd-catalyzed cross-coupling of allylsilane-vinylcopper species with aryl and vinyl halides: the first total synthesis of (-)-nomadone
Francisco J. Pulido, Asunción Barbero, Carlos García
Tetrahedron 2009, 65, 5535-5540
Intramolecular carbonyl-ene reactions in allylsilanes
Asunción Barbero, Francisco J. Pulido, Mª Carmen Sañudo
ARKIVOC 2007, (iv), 220-233
Peterson olefination from alfa-silyl aldehydes
Francisco J. Pulido, Asunción Barbero
Nature Protocols, 2006, 1, 2068-2074
Allylstannanes and vinylstannanes from stannylcupration of C-C multiple bonds. Recent advances and applications in organic synthesis
Asunción Barbero, Francisco J. Pulido
Chem. Soc. Rev., 2005, 34, 913-920
Intramolecular ene reaction of epoxyallylsilanes: Synthesis of allyl- and vinylsilane-functionalized cyclohexanols
Asunción Barbero, Pilar Castreño, Gloria Fernandez, Francisco J. Pulido
J. Org. Chem., 2005, 70, 10747-10752
Silylcuprates from allene and their reaction with alpha,beta-unsaturated nitriles and imines. Synthesis of silylated oxo compounds leading to cyclopentane and cycloheptane ring formation
Asunción Barbero, Yolanda Blanco, Francisco J. Pulido
J. Org. Chem., 2005, 70, 6876-6883
Spiro-cyclopropanation from oxoallylsilanes
Asunción Barbero, Pilar Castreño, Francisco J. Pulido
J. Am. Chem. Soc., 2005, 127, 8022-8023
Allene: As small in size as versatile in synthesis. A general scope of its usefulness as a C-3-synthon for carbocyclic annulations Asunción Barbero, Francisco J. Pulido
Allylsilanes and vinylsilanes from silylcupration of carbon-carbon multiple bonds: Scope and synthetic applications
Asunción Barbero, Francisco J. Pulido
Acc. Chem. Res., 2004, 37, 817-825
Acid-catalyzed cyclization of epoxyallylsilanes. An unusual rearrangement cyclization process
Asunción Barbero, Pilar Castreño, Francisco J. Pulido
Org. Lett., 2003, 5, 4045-4048
Addition of organometallic compounds to tin-containing cyclic ketones. Remote stereocontrol induced by the stannyl group
Asunción Barbero, Francisco J. Pulido, Juan A. Rincón
J. Am. Chem. Soc., 2003, 125, 1209-12056
A tandem allylsilane-vinylsilane difunctionalization by silylcupration of allene followed by reaction with alpha,beta-unsaturated nitriles
Asunción Barbero, Yolanda Blanco, Francisco J. Pulido
Chem. Commun., 2001, 1606-1607
Allylsilane-Vinylcopper Reagents: Palladium Mediated Coupling with Alkenyl Halides. Synthesis and [2+2] Cyclization of (+)-Ipsdienol
Asunción Barbero, Carlos García, Francisco J. Pulido
Synlett 2001, 824-826
Allylsilane-vinylcopper reagents: Palladium-mediated coupling with alkenyl halides. Synthesis and photochemical [2+2] cyclization of (+/-)-Ipsdienol
Asunción Barbero, Carlos García, Francisco J. Pulido
Synlett 2001, 827-829
Intramolecular cyclization of tert-butyldiphenylallylsilane units and carbonyl groups: Allylsilane terminated cyclization versus the ene reaction
Asunción Barbero, Pilar Castreño, Carlos García, Francisco J. Pulido.
J. Org. Chem., 2001, 66, 7723-7728
Remote stereocontrol in carbonyl additions promoted by vinylstannanes
Asunción Barbero, Francisco J. Pulido, Juan A. Rincón, Purificación Cuadrado, Diego Galisteo, Henar Martínez-García
Angew. Chem. Int. Ed. 2001,40, 2101-2103
Functionalised allylsilanes from silylcopper reagents and allene. A useful strategy for cyclopentane annulation
Asunción Barbero, Carlos García, Francisco J. Pulido.
Tetrahedron 2000, 56, 2739-2751
Silylcupration of allenes followed by reaction with enones: A new strategy for the synthesis of methylenecyclopentanols
Asunción Barbero, Carlos García, Francisco J. Pulido
Tetrahedron Lett. 1999,40, 6649-6652
Stannylcupration of acetylenes followed by reaction with epoxides: A novel annulation strategy for the synthesis of cyclobutenes
Asunción Barbero, Purificación Cuadrado, Carlos García, Francisco J. Pulido, Juan A. Rincón
J. Org. Chem. 1998, 63, 7531-7533
Stereochemical control in organic synthesis using silicon-containing compounds
Ian Fleming, Asunción Barbero, David Walter
Chem. Rev. 1997, 97, 2063-2192
In search of open-chain 1,3-sterocontrol
Asunción Barbero, David C. Blakemore, Ian Fleming, Robert N. Wesley
J. Chem. Soc., Perkin Trans. I 1997, 1329-1352
Open chain 1,3-sterocontrol
Asunción Barbero, David C. Blakemore, Ian Fleming, Robert N. Wesley
Pure Appl. Chem. 1996, 68, 585-588